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Slack / Private Message Drop, pp.436-437 [SLACK_000650] · slack_pm:msg:04512

Page text: p.436, p.437 · original PDF

Date
2021-01-22 11:50
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

Recipients on this medium are inferred from channel membership, not per-message addressing.

From Weifeng and obviously in very strict confidence. I assume these are from Yunnan. Also has some interesting alphas.

In context

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  1. 2021-01-22 11:12 Kristian G. Andersen open
    @Kristian Andersen Yeah. I'm going more with it showing up both in RSA and BRA and the RSA paper showing that the NTD mutations are important for escape.
  2. 2021-01-22 11:45 Robert F. Garry open
    @Kristian Andersen Yeah - NTD is definitely doing something we are not yet accounting for.
  3. 2021-01-22 11:47 Andrew Rambaut open
    I am not sure it is that strong. But the report was leaked so they had to do the press. It is really hard to tease apart all the confounding factors.
  4. 2021-01-22 11:49 Edward C. Holmes open
    This largely speaks for itself: [shared file(s): FigXX_B_Beta_MSA_v2.2_RdRp.pdf, FigXX_A_Beta_MSA_v2.2_Full length genome.pdf, all_similarity.xlsx]
  5. 2021-01-22 11:50 Edward C. Holmes
    From Weifeng and obviously in very strict confidence. I assume these are from Yunnan. Also has some interesting alphas.
  6. 2021-01-22 11:54 Kristian G. Andersen open
    Oh, very interesting! Looking forward to seeing the actual sequences. Very cool.
  7. 2021-01-22 11:57 Edward C. Holmes open
    The similarity scores imply that some are as close as RaTG13 in a number of genes. Will be good to see the Cambodian one in this tree as well. Interesting recombination events with respect to the pangolin viruses. Nature isan amazing thing.
  8. 2021-01-22 12:13 Kristian G. Andersen open
    What's interesting is that it's all over the place every time we find a new virus. We're only scratching 0.000000000000000000000000000000001% of the surface.
  9. 2021-01-22 12:21 Edward C. Holmes open
    Exactly. So many viruses in nature that are close to SARS-CoV-2.

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