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Slack / Private Message Drop, p.436 [SLACK_000650] · slack_pm:msg:04509

Page text: p.436 · original PDF

Date
2021-01-22 11:45
Type
chat message · slack
mentioned
Kristian G. Andersen
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

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@Kristian Andersen Yeah - NTD is definitely doing something we are not yet accounting for.

In context

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  1. 2021-01-22 11:07 Kristian G. Andersen open
    @Andrew Rambaut - how good is the data on the increased mortality from B.1.1.7? Makes sense it would be, however, comparing mortality rates during a surge is problematic....
  2. 2021-01-22 11:09 Robert F. Garry open
    @Kristian Andersen L18F is not in the cryo structure, but it is likely in the NTD near where delHV and the del around241-3 in the mink.
  3. 2021-01-22 11:12 Kristian G. Andersen open
    @Kristian Andersen Yeah. I'm going more with it showing up both in RSA and BRA and the RSA paper showing that the NTD mutations are important for escape.
  4. 2021-01-22 11:45 Robert F. Garry
    @Kristian Andersen Yeah - NTD is definitely doing something we are not yet accounting for.
  5. 2021-01-22 11:47 Andrew Rambaut open
    I am not sure it is that strong. But the report was leaked so they had to do the press. It is really hard to tease apart all the confounding factors.
  6. 2021-01-22 11:49 Edward C. Holmes open
    This largely speaks for itself: [shared file(s): FigXX_B_Beta_MSA_v2.2_RdRp.pdf, FigXX_A_Beta_MSA_v2.2_Full length genome.pdf, all_similarity.xlsx]
  7. 2021-01-22 11:50 Edward C. Holmes open
    From Weifeng and obviously in very strict confidence. I assume these are from Yunnan. Also has some interesting alphas.
  8. 2021-01-22 11:54 Kristian G. Andersen open
    Oh, very interesting! Looking forward to seeing the actual sequences. Very cool.

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