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Slack / Private Message Drop, p.437 [SLACK_000651] · slack_pm:msg:04515

Date: 2021-01-22 12:13
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

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What's interesting is that it's all over the place every time we find a new virus. We're only scratching 0.000000000000000000000000000000001% of the surface.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-01-22 11:49 Edward C. Holmes open

This largely speaks for itself: [shared file(s): FigXX_B_Beta_MSA_v2.2_RdRp.pdf, FigXX_A_Beta_MSA_v2.2_Full length genome.pdf, all_similarity.xlsx]
2021-01-22 11:50 Edward C. Holmes open

From Weifeng and obviously in very strict confidence. I assume these are from Yunnan. Also has some interesting alphas.
2021-01-22 11:54 Kristian G. Andersen open

Oh, very interesting! Looking forward to seeing the actual sequences. Very cool.
2021-01-22 11:57 Edward C. Holmes open

The similarity scores imply that some are as close as RaTG13 in a number of genes. Will be good to see the Cambodian one in this tree as well. Interesting recombination events with respect to the pangolin viruses. Nature isan amazing thing.
2021-01-22 12:13 Kristian G. Andersen

What's interesting is that it's all over the place every time we find a new virus. We're only scratching 0.000000000000000000000000000000001% of the surface.
2021-01-22 12:21 Edward C. Holmes open

Exactly. So many viruses in nature that are close to SARS-CoV-2.
2021-01-22 12:21 Edward C. Holmes open

Take a look @Andrew Rambaut and @Robert Garry
2021-01-22 12:24 Robert F. Garry open

Very interesting- how about the S1/S2 junction - HA379_CNSv1 seems close to RmYN02 - Maybe it and perhaps the other have indels there?
2021-01-22 12:24 Robert F. Garry open

@Kristian Andersen BTW - nice chart there @Kristian Andersen

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