A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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She's a 1000X times tougher than me. I find it very difficult and have to get off social media as much as I can. I also hate dealing with the mainstream media. She must get endless shit. No idea how she manages it.
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Angie is indeed tough as nails - true hero! I *do* wonder if she has a hard time dealing with all the shit she must begetting - she _is_ moving to Canada after all. Can't blame for for leaving this dumpster fire - I'd do the same in aheartbeat if anybody up north wanted me.
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There's an opening at the Wuhan Institute of Virology. Labs were recently renovated and cleaned.
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> Yes - they do. But I think they can't get there by progressive steps in sequential infections - there are troughs(we see all of these mutations appear individually many times). Agreed. The way I'm thinking about this is that there must be an initial selection pressure that drives the fixation ofthose mutations - almost certainly, that selection pressure is intrahost. Once that variant is out - and it's more transmissible / able to evade immunity - then it's a different selection pressure driving its fixation in the population. Itoo just think there's a really unfortunate relationship between really fit intrahost, means you're really fit in the larger population. Separately, two vaccine failures en route to our lab - I sure as shit hope these are not B117! (they'reepidemiologically connected...).
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2021-01-14 16:14
Andrew Rambaut
How long after vaccination?
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I believe this was just after receiving second shots - but importantly, in the presence of strong IgG anti-S titers.
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Don't know if these titers are neuts though - something we need to test. We have a bunch inbound from Jordan too, but those are failures from one of the Chinese vaccines.
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All vaccine failures in the UK will automatically go for sequencing - I am hopeful we will be told which ones they are but who knows.
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Yeah, going to be really important over the next couple of months to understand what's going on here. The immunologists seem very (VERY!) sure there is no problem with the UK/RSA/Brazil lineages when it comes to immunity. I'm less certain.