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Slack / Private Message Drop, p.399 [SLACK_000613] · slack_pm:msg:04121

Page text: p.399 · original PDF

Date
2021-01-14 15:58
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes
Topics
Intelligence community assessments

Recipients on this medium are inferred from channel membership, not per-message addressing.

She's a 1000X times tougher than me. I find it very difficult and have to get off social media as much as I can. I also hate dealing with the mainstream media. She must get endless shit. No idea how she manages it.

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StatementGradeAttributionStance
I find it very difficult and have to get off social media as much as I can. own voice, substantive speaker_own asserts

In context

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  1. 2021-01-14 15:46 Andrew Rambaut open
    Yes - they do. But I think they can't get there by progressive steps in sequential infections - there are troughs (wesee all of these mutations appear individually many times).
  2. 2021-01-14 15:47 Andrew Rambaut open
    So the chronic infections offer an opportunity for these to arise in combination. Chronic infections are rare as aproportion of infections but there are shed loads of infections now.
  3. 2021-01-14 15:47 Edward C. Holmes open
    Indeed. Not saying the theory is wrong, just that there are some loose ends. I can only imagine how Alina and ganghave reacted to this: [shared file(s): s41591-020-01205-5.pdf]
  4. 2021-01-14 15:54 Andrew Rambaut open
    Nice piece. Angie is a true hero. I can't imagine what she must put up with (you probably can more than me, Eddie, but women get it so much worse).
  5. 2021-01-14 15:58 Edward C. Holmes
    She's a 1000X times tougher than me. I find it very difficult and have to get off social media as much as I can. I also hate dealing with the mainstream media. She must get endless shit. No idea how she manages it.
  6. 2021-01-14 16:03 Kristian G. Andersen open
    Angie is indeed tough as nails - true hero! I *do* wonder if she has a hard time dealing with all the shit she must begetting - she _is_ moving to Canada after all. Can't blame for for leaving this dumpster fire - I'd do the same in aheartbeat if anybody up north wanted me.
  7. 2021-01-14 16:04 Edward C. Holmes open
    There's an opening at the Wuhan Institute of Virology. Labs were recently renovated and cleaned.
  8. 2021-01-14 16:06 Kristian G. Andersen open
    > Yes - they do. But I think they can't get there by progressive steps in sequential infections - there are troughs(we see all of these mutations appear individually many times). Agreed. The way I'm thinking about this is that there must be an initial selection pressure that drives the fixation ofthose mutations - almost certainly, that selection pressure is intrahost. Once that variant is out - and it's more transmissible / able to evade immunity - then it's a different selection pressure driving its fixation in the population. Itoo just think there's a really unfortunate relationship between really fit intrahost, means you're really fit in the larger population. Separately, two vaccine failures en route to our lab - I sure as shit hope these are not B117! (they'reepidemiologically connected...).
  9. 2021-01-14 16:14 Andrew Rambaut open
    How long after vaccination?

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