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Slack / Private Message Drop, pp.576-577 [SLACK_000790] · slack_pm:msg:06021

Page text: p.576, p.577 · original PDF

Date
2021-03-08 15:07
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

Recipients on this medium are inferred from channel membership, not per-message addressing.

I think they assume - 10,000 samples = 10,000 chances for SC2 to hop out of a tube. Nope.

In context

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  1. 2021-03-08 15:04 Robert F. Garry open
    Explains some of the problems in the diagnostic space - Start mixing in detection with antigen assays [which correlates not so well with infectious virus or RNA] and it gets complicated fast.
  2. 2021-03-08 15:06 Andrew Rambaut open
    But that means these ideas about WIV sampling viruses from the wild and one of the accidentally escapes might bewrong?
  3. 2021-03-08 15:07 Kristian G. Andersen open
    I think most of those people underestimate how incredibly hard it is to grow stuff from such samples, yes.
  4. 2021-03-08 15:07 Robert F. Garry open
    Screening species with serology though I think is the way to go - that is why Lin-Fa's ACE2BOB makes sense - find the species that have antibodies then trap the hell out of them until you get lucky and hit one at peak viremia/RNA.
  5. 2021-03-08 15:07 Kristian G. Andersen
    I think they assume - 10,000 samples = 10,000 chances for SC2 to hop out of a tube. Nope.
  6. 2021-03-08 15:08 Robert F. Garry open
    @Andrew Rambaut Hammer hits nail!
  7. 2021-03-08 15:09 Kristian G. Andersen open
    There's virtually _zero_ chance a virus could leak out of a tube - if they culture to high titers, sure - but again, in most circumstances that's not going to be possible because it's so hard to grow anything out of a primary sample.
  8. 2021-03-08 15:11 Robert F. Garry open
    That and they should be doing it with at least an N95 and better yet a PAPR. Damn sure have my ppl in a PAPR/class 2 hood if they are trying to grow virus in large amts.
  9. 2021-03-08 15:12 Kristian G. Andersen open
    Yes, Bob, but these are Chinese scientists - they're clueless, you know.

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