A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Yeah, culturing viruses from bats or any other animal = bloody hard. I wouldn't be surprised that if you had 50 bats all infected with SC2, you'd only be able to grow it out of one of those.
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Explains some of the problems in the diagnostic space - Start mixing in detection with antigen assays [which correlates not so well with infectious virus or RNA] and it gets complicated fast.
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But that means these ideas about WIV sampling viruses from the wild and one of the accidentally escapes might bewrong?
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I think most of those people underestimate how incredibly hard it is to grow stuff from such samples, yes.
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2021-03-08 15:07
Robert F. Garry
Screening species with serology though I think is the way to go - that is why Lin-Fa's ACE2BOB makes sense - find the species that have antibodies then trap the hell out of them until you get lucky and hit one at peak viremia/RNA.
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I think they assume - 10,000 samples = 10,000 chances for SC2 to hop out of a tube. Nope.
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@Andrew Rambaut Hammer hits nail!
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There's virtually _zero_ chance a virus could leak out of a tube - if they culture to high titers, sure - but again, in most circumstances that's not going to be possible because it's so hard to grow anything out of a primary sample.
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That and they should be doing it with at least an N95 and better yet a PAPR. Damn sure have my ppl in a PAPR/class 2 hood if they are trying to grow virus in large amts.