COVID-19 Records

Chat message

Slack / Private Message Drop, p.1026 [SLACK_001240] · slack_pm:msg:10723

Page text: p.1026 · original PDF

Date
2021-11-24 08:50
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

Recipients on this medium are inferred from channel membership, not per-message addressing.

So if you were going to pick a virus from amongst your large bank of samples in which to try popping a FCS insertion you would pick out one with QTQT?

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

  1. 2021-11-24 08:46 Kristian G. Andersen open
    Yup - almost looks step-wise.
  2. 2021-11-24 08:46 Robert F. Garry open
    Indeed - that's always puzzled me.
  3. 2021-11-24 08:48 Andrew Rambaut open
    What would it do without the PRRA insert?
  4. 2021-11-24 08:48 Robert F. Garry open
    I've think that the enzymes that do the cleavage at R/S also probably benefit by having a "landing pad."
  5. 2021-11-24 08:50 Andrew Rambaut
    So if you were going to pick a virus from amongst your large bank of samples in which to try popping a FCS insertion you would pick out one with QTQT?
  6. 2021-11-24 08:52 Robert F. Garry open
    Not without having all the knowledge in hindsight.
  7. 2021-11-24 08:52 Andrew Rambaut open
    Fair enough. I won't tweet that then.
  8. 2021-11-24 08:52 Robert F. Garry open
    Same argument with the O-linked glycans - without having SC2 as the guidepost - you would not know....
  9. 2021-11-24 08:53 Robert F. Garry open
    Good - that would just encourage the Leakers...

Full conversation →