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Slack / Private Message Drop, p.496 [SLACK_000710] · slack_pm:msg:05173

Page text: p.496 · original PDF

Date
2021-02-07 12:29
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

Recipients on this medium are inferred from channel membership, not per-message addressing.

Or the serum - do they know the genotype of the donor?

In context

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  1. 2021-02-07 12:25 Kristian G. Andersen open
    I think Leif and Karen are key too - but I'd expect B.1.1.7 + Erik to come with a big hit too.
  2. 2021-02-07 12:26 Kristian G. Andersen open
    Absolutely no effect preventing mild-moderate so I don't expect much ability to prevent severe either. But we'll see -this is very early data. It's just a shit vaccine - I'm sure the others won't see this bad a drop (and we have _some_ data on that) and will also prevent severe disease in many cases.
  3. 2021-02-07 12:28 Andrew Rambaut open
    Leif is everywhere (and quite common on B.1.1.7)
  4. 2021-02-07 12:29 Andrew Rambaut open
    When testing vaccines against B.1.351, are they using one with Leif and Karen?
  5. 2021-02-07 12:29 Andrew Rambaut
    Or the serum - do they know the genotype of the donor?
  6. 2021-02-07 12:30 Robert F. Garry open
    https://docs.google.com/document/d/17-2hi7-fNsjE44himeCkm1PoZ7_-ncvpxUlhShZzDCU/edit On another note - I just popped a *nearly clean draft* of a proposed Virological post about Cambodian, Thai and Japanese bat sarbecoviruses. It's actually pretty mild, but Alina etc. *do* get attention. I borrowed VERY heavily from this channel,so please let me know if you are co-authors or I can go solo...
  7. 2021-02-07 12:30 Kristian G. Andersen open
    These are clinical trials - so wildtype
  8. 2021-02-07 12:31 Kristian G. Andersen open
    What's critically important here - drop in efficacy, even bigger than drop observed in vitro
  9. 2021-02-07 12:31 Kristian G. Andersen open
    (which is not surprising to me)

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