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Slack / Private Message Drop, p.383 [SLACK_000597] · slack_pm:msg:03984

Page text: p.383 · original PDF

Date
2021-01-11 15:18
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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Yeah - high... (although I saw quite a number of people disagreeing with that number and the IFR seemed too low tome)

In context

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  1. 2021-01-11 15:16 Andrew Rambaut open
    Not yet. Fiacruz has one case of reinfection (not this lineage - but another with 484K)
  2. 2021-01-11 15:17 Andrew Rambaut open
    Latest UK estimate is a total number of infections as 20% of population.
  3. 2021-01-11 15:17 Kristian G. Andersen open
    Okie dokie - will be important/interesting to know. Also very curious to see what's going to happen in Israel after thevax campaign.
  4. 2021-01-11 15:17 Andrew Rambaut open
    Manaus estimated at 60-70% from first wave
  5. 2021-01-11 15:18 Kristian G. Andersen
    Yeah - high... (although I saw quite a number of people disagreeing with that number and the IFR seemed too low tome)
  6. 2021-01-11 15:18 Andrew Rambaut open
    South Africa high but the area where the variant took off is really high - urban, dense, deprived.
  7. 2021-01-11 15:21 Kristian G. Andersen open
    Yup - seems plausible that immune escape might be the most likely explanation here - whether linked to natural immunity or vaccine induced. Why that would lead to increased transmission, I'm not quite sure I understand - except if e.g., high ACE2 binding is associated with both escape and transmission (not implausible).
  8. 2021-01-11 15:24 Kristian G. Andersen open
    It's all very interesting - although to be honest, I don't need any additional excitement at the moment. I just want toget back to being a totally anonymous scientist (with 323 followers on Twitter) looking at Ebola and Lassa genomes. SARS-CoV-2 is a little too exciting for my liking.
  9. 2021-01-11 15:30 Andrew Rambaut open
    It could be that the UK one is the only one that is inherently more transmissible (perhaps because of the 681H?).The other two are only taking off in hi-prevalence areas. We will see as more of those arrive in much lowerprevalence areas

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