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Slack / Private Message Drop, p.383 [SLACK_000597] · slack_pm:msg:03983

Page text: p.383 · original PDF

Date
2021-01-11 15:17
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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Manaus estimated at 60-70% from first wave

In context

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  1. 2021-01-11 15:16 Kristian G. Andersen open
    Does Oli/Nuno have any data on reinfections? You mentioned a Virological study yesterday, but not sure if they're looking at that?
  2. 2021-01-11 15:16 Andrew Rambaut open
    Not yet. Fiacruz has one case of reinfection (not this lineage - but another with 484K)
  3. 2021-01-11 15:17 Andrew Rambaut open
    Latest UK estimate is a total number of infections as 20% of population.
  4. 2021-01-11 15:17 Kristian G. Andersen open
    Okie dokie - will be important/interesting to know. Also very curious to see what's going to happen in Israel after thevax campaign.
  5. 2021-01-11 15:17 Andrew Rambaut
    Manaus estimated at 60-70% from first wave
  6. 2021-01-11 15:18 Kristian G. Andersen open
    Yeah - high... (although I saw quite a number of people disagreeing with that number and the IFR seemed too low tome)
  7. 2021-01-11 15:18 Andrew Rambaut open
    South Africa high but the area where the variant took off is really high - urban, dense, deprived.
  8. 2021-01-11 15:21 Kristian G. Andersen open
    Yup - seems plausible that immune escape might be the most likely explanation here - whether linked to natural immunity or vaccine induced. Why that would lead to increased transmission, I'm not quite sure I understand - except if e.g., high ACE2 binding is associated with both escape and transmission (not implausible).
  9. 2021-01-11 15:24 Kristian G. Andersen open
    It's all very interesting - although to be honest, I don't need any additional excitement at the moment. I just want toget back to being a totally anonymous scientist (with 323 followers on Twitter) looking at Ebola and Lassa genomes. SARS-CoV-2 is a little too exciting for my liking.

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