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Slack / Private Message Drop, p.296 [SLACK_000510] · slack_pm:msg:03087

Recipients on this medium are inferred from channel membership, not per-message addressing.

Lemme include that too - and I should say, all those calls are fully supported in the RaTG13 assembly, so they're good

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-12-06 09:55 Kristian G. Andersen open

There are some low-coverage regions in that genome where you have ambiguous calls
2020-12-06 10:02 Kristian G. Andersen open

Just compared WA1 to Hu-1 and RaTG13. Only three differences between the two, all of them ancestral in WA1 - not Hu-1.
2020-12-06 10:02 Kristian G. Andersen open

What do you use as prototypical Lineage A?
2020-12-06 10:03 Andrew Rambaut open

WH04
2020-12-06 10:03 Kristian G. Andersen

Lemme include that too - and I should say, all those calls are fully supported in the RaTG13 assembly, so they're good
2020-12-06 10:04 Kristian G. Andersen open

It's that midpoint root.... Some early emergence funkiness.
2020-12-06 10:06 Kristian G. Andersen open

I have WH04 being identical to Hu-1, except the ends - do you have a different sequence?
2020-12-06 10:08 Andrew Rambaut open

Hu-1 should have 2 differences from WH04 (EPI_ISL_406801): T:8781:C, C:28143:T
2020-12-06 10:11 Andrew Rambaut open

Wuhan-Hu-1: T:8781:C|T:18059:C|C:28143:T WH04: T:18059:C WA1: 0: