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Slack / Private Message Drop, p.297 [SLACK_000511] · slack_pm:msg:03091

Page text: p.297 · original PDF

Date
2020-12-06 10:11
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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Wuhan-Hu-1: T:8781:C|T:18059:C|C:28143:T WH04: T:18059:C WA1: 0:

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  1. 2020-12-06 10:03 Kristian G. Andersen open
    Lemme include that too - and I should say, all those calls are fully supported in the RaTG13 assembly, so they're good
  2. 2020-12-06 10:04 Kristian G. Andersen open
    It's that midpoint root.... Some early emergence funkiness.
  3. 2020-12-06 10:06 Kristian G. Andersen open
    I have WH04 being identical to Hu-1, except the ends - do you have a different sequence?
  4. 2020-12-06 10:08 Andrew Rambaut open
    Hu-1 should have 2 differences from WH04 (EPI_ISL_406801): T:8781:C, C:28143:T
  5. 2020-12-06 10:11 Andrew Rambaut
    Wuhan-Hu-1: T:8781:C|T:18059:C|C:28143:T WH04: T:18059:C WA1: 0:
  6. 2020-12-06 10:11 Kristian G. Andersen open
    The version I have of Hu-1 (MN908947) is identical - weird... Lemme check again
  7. 2020-12-06 10:13 Kristian G. Andersen open
    Yup, identical based on NCBI records (except the ends). Here's the Geneious alignment [shared file(s): 2020.12.06_alignment.geneious]
  8. 2020-12-06 10:13 Kristian G. Andersen open
    WA1 has three differences to both WH04 and Hu-1 - all three ancestral.
  9. 2020-12-06 10:15 Kristian G. Andersen open
    Lemme check these human sequences against the larger pango/bat alignment I have - since I have all the assemblies for those too.

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