A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Here's the reference for the FCS control: https://pubmed.ncbi.nlm.nih.gov/28924042/
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Yes - very pertinent which means I need to add this reference and you as a co-author -you already pointed me to the feline CoVs OK? Also OK to add Andrew and Eddie in acknowledgents for helpful discussions and encouragement?Alternatively I think Andrew and Eddie rise to authorship as well - putting all the PO1 authors on minus Ian but plus Prof Bill in A Virological would certainly garner some attention and stir up the Chan, Yan , Relman and Billy krewe.
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I think this is a clear Bob Garry investigation, so no need to add me - but yeah, add us all in acknowledgments :wink:
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[unless you're scared to face the trolls on your own... :wink: ]
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2020-11-21 08:04
Andrew Rambaut
It would be interesting to test an SC2 with a FCS deletion in ferrets
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Agreed - Bob and I have discussed these types of experiments previously. Would also be important to do the same in e.g., human lung cells. Don't know if there's an isolate without the FCS though?
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The deletion is nonpathogenic in hamsters, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457603/ but yes ferret abetter model. Tulane primate center and other doing monkeys but I don't know latest results.
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Yeah, ferrets better - and question is - will it pick it up if passaged in ferrets? I bet this whole thing could easily relateto farming of mustelids.