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Slack / Private Message Drop, p.271 [SLACK_000485] · slack_pm:msg:02822

Date: 2020-11-21 08:13
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

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Yeah, ferrets better - and question is - will it pick it up if passaged in ferrets? I bet this whole thing could easily relateto farming of mustelids.

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2020-11-21 08:04 Kristian G. Andersen open

[unless you're scared to face the trolls on your own... :wink: ]
2020-11-21 08:04 Andrew Rambaut open

It would be interesting to test an SC2 with a FCS deletion in ferrets
2020-11-21 08:06 Kristian G. Andersen open

Agreed - Bob and I have discussed these types of experiments previously. Would also be important to do the same in e.g., human lung cells. Don't know if there's an isolate without the FCS though?
2020-11-21 08:12 Robert F. Garry open

The deletion is nonpathogenic in hamsters, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457603/ but yes ferret abetter model. Tulane primate center and other doing monkeys but I don't know latest results.
2020-11-21 08:13 Kristian G. Andersen

Yeah, ferrets better - and question is - will it pick it up if passaged in ferrets? I bet this whole thing could easily relateto farming of mustelids.

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