Chat message

Slack / Private Message Drop, p.271 [SLACK_000485] · slack_pm:msg:02820

Date: 2020-11-21 08:06
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

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Agreed - Bob and I have discussed these types of experiments previously. Would also be important to do the same in e.g., human lung cells. Don't know if there's an isolate without the FCS though?

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-11-21 07:57 Robert F. Garry open

Yes - very pertinent which means I need to add this reference and you as a co-author -you already pointed me to the feline CoVs OK? Also OK to add Andrew and Eddie in acknowledgents for helpful discussions and encouragement?Alternatively I think Andrew and Eddie rise to authorship as well - putting all the PO1 authors on minus Ian but plus Prof Bill in A Virological would certainly garner some attention and stir up the Chan, Yan , Relman and Billy krewe.
2020-11-21 08:03 Kristian G. Andersen open

I think this is a clear Bob Garry investigation, so no need to add me - but yeah, add us all in acknowledgments :wink:
2020-11-21 08:04 Kristian G. Andersen open

[unless you're scared to face the trolls on your own... :wink: ]
2020-11-21 08:04 Andrew Rambaut open

It would be interesting to test an SC2 with a FCS deletion in ferrets
2020-11-21 08:06 Kristian G. Andersen

Agreed - Bob and I have discussed these types of experiments previously. Would also be important to do the same in e.g., human lung cells. Don't know if there's an isolate without the FCS though?
2020-11-21 08:12 Robert F. Garry open

The deletion is nonpathogenic in hamsters, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457603/ but yes ferret abetter model. Tulane primate center and other doing monkeys but I don't know latest results.
2020-11-21 08:13 Kristian G. Andersen open

Yeah, ferrets better - and question is - will it pick it up if passaged in ferrets? I bet this whole thing could easily relateto farming of mustelids.

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