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Slack / Private Message Drop, p.92 [SLACK_000306] · slack_pm:msg:00937

Page text: p.92 · original PDF

Date
2020-07-01 15:02
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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Please don't show this to anyone just yet but here is an analysis by Erik Volz and we are backing this up on the same data with different models. [shared file(s): image.png]

In context

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  1. 2020-07-01 14:24 Edward C. Holmes open
    If the Editor is completely on the side of the authors what can you do? Their's peer reviewer and then ignoring peer review. Clearly Cell wanted it accepted ASAP because they were worried about being scooped and wanted thecitations. Here's the 1st major comment from my review "The statistical analysis of the D614G variant is flawed. I'm not saying that the conclusion is wrong, but the analysis is."
  2. 2020-07-01 14:30 Edward C. Holmes open
    I'll use those grader quotes in my next review.
  3. 2020-07-01 15:00 Andrew Rambaut open
    Our analysis of the UK data seems to suggest a higher rate of G growth but it is really hard. We consistently get ahigher rate but the significance depends on the details of the analyses. The effect size is small but not insignificant(if true). On the other hand there is not much you can do with the knowledge.
  4. 2020-07-01 15:02 Kristian G. Andersen open
    Do you have a visual of any of this? I'm kinda struggling with how a difference like this might even look like. The previous R0 estimates I saw for the two clades from Trevor's group essentially looked identical
  5. 2020-07-01 15:02 Andrew Rambaut
    Please don't show this to anyone just yet but here is an analysis by Erik Volz and we are backing this up on the same data with different models. [shared file(s): image.png]
  6. 2020-07-01 15:03 Andrew Rambaut open
    Each dot is in an independent introduction into the UK.
  7. 2020-07-01 15:03 Kristian G. Andersen open
    And how's growth rate calculated?
  8. 2020-07-01 15:03 Andrew Rambaut open
    But basically this is not significant under most conservative conditions.
  9. 2020-07-01 15:05 Andrew Rambaut open
    This is using Erik's skygrowth model.

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