Slack / Private Message Drop — page 82

[Andrew Rambaut] 3 Beijing ones (one environmental). Two have 1 unique mutation each and one has 2. [2020-06-18 09:26:02] [Robert Garry] Definitely explains the salmon connection - Pompeo is all over this - M15 too :laughing: [shared file(s): 659bbfd59640355daafa23a259532eab.png] [2020-06-18 10:37:18] [Kristian Andersen] [thread - ID: 2020-06-18 10:37:18] Hmmm - those TMRCAs are a lot older than I expected. Since that's driven by so few mutations, do we believe all SNPs are real? [2020-06-18 10:37:47] [Kristian Andersen] And yeah - clearly Denmark :wink: [2020-06-18 15:15:34] [Eddie Holmes] In basements all over the world people will be looking at Google Maps and drawing straight lines between the fish market and the China CDC head office in Beijing. [2020-06-18 15:22:38] [Kristian Andersen] Haha [2020-06-18 15:38:24] [Andrew Rambaut] [thread - ID: 2020-06-18 10:37:18] I don't really know. I think they all come from the market (1 environmental and 2 people) on the same day so it seems unlikely. Unless this is much bigger than they think. [2020-06-18 15:39:51] [Andrew Rambaut] You probably saw it but here is the ML tree (with an outgroup root): [shared file(s): beijing_11.ml.tree.png] [2020-06-18 15:40:32] [Andrew Rambaut] Weird that the one of them is at the base of that polytomy. [2020-06-18 15:42:55] [Kristian Andersen] Yeah, it's very interesting. Is it really possibly Beijing has had an outbreak for quite some time? As in at least a few weeks? I have been trying to create an alignment to look at the individual mutation for the last few hours - I can't deal with how big the data is these days... :wink: [2020-06-18 15:46:21] [Andrew Rambaut] Plausible: https://www.theguardian.com/world/2020/jun/18/global-report-beijing-covid-19-cluster-may-have-begun-amonth-earlier-china-health-chief [2020-06-18 15:47:57]