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Slack / Private Message Drop, p.1026 [SLACK_001240] · slack_pm:msg:10717

Page text: p.1026 · original PDF

Date
2021-11-24 08:43
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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For the non-SC2 viruses they _either_ have QTQT _or_ the indel - but not both. SC2 has both.

In context

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  1. 2021-11-24 08:37 Kristian G. Andersen open
    Yup. QTQT is a landing site?
  2. 2021-11-24 08:40 Robert F. Garry open
    yes both are neutral polar animo acids
  3. 2021-11-24 08:42 Andrew Rambaut open
    I assume you say it cutie-cutie?
  4. 2021-11-24 08:42 Kristian G. Andersen open
    I had missed that previously, but that's actually kinda interesting - because: [shared file(s): furin_aa_nov21.png]
  5. 2021-11-24 08:43 Kristian G. Andersen
    For the non-SC2 viruses they _either_ have QTQT _or_ the indel - but not both. SC2 has both.
  6. 2021-11-24 08:45 Andrew Rambaut open
    The RmYN02-like are quite distant to SC2 in this bit of the genome. Is it not more interesting that RaTG13/BANAL-20-52-like viruses acquired the QTQT motif?
  7. 2021-11-24 08:46 Kristian G. Andersen open
    Yup - almost looks step-wise.
  8. 2021-11-24 08:46 Robert F. Garry open
    Indeed - that's always puzzled me.
  9. 2021-11-24 08:48 Andrew Rambaut open
    What would it do without the PRRA insert?

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