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Slack / Private Message Drop, p.947 [SLACK_001161] · slack_pm:msg:09858

Page text: p.947 · original PDF

Date
2021-06-19 14:52
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes
Topics
Natural origin / zoonotic spillover

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It's a weird sort of stream of consciousness paper. Very naughty to include an email from the unrelated pangolin study in there. Is that even legal?

In context

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  1. 2021-06-19 14:44 Robert F. Garry open
    "The second explanation, which was proposed in a blog post by Garry (2021) and amplified by a popular podcast (Racaniello _et al._ 2021), is that there were multiple zoonoses from distinct markets, with the Huanan Seafood Market being the source of viruses in clade B, and some other market being the source of viruses that lack the T8782C and C28144T mutations. However, inspection of Fig- ure 4 shows that clade B is connected to viruses lacking T8782C and C28144T by single mutational steps via other human iso- lates, so this explanation requires not only positing two markets with two progenitors differing by just two mutations, but also the exceedingly improbableevolution of one of these progenitors towards the other after it had jumped to humans." Actually no - simple to see how the mutations might have become fixed in the progression -I think the take-home is JB is dead set that Rambautis wrong and actually B came before A. Because? [shared file(s): image.png]
  2. 2021-06-19 14:45 Edward C. Holmes open
    Is this something or nothing? I can't quite get my head around it.
  3. 2021-06-19 14:49 Robert F. Garry open
    I think JB main point is they removed some SRA data re early cases - the data IMO - and maybe I can be shown the error of my ways - adds basically zero. It allows JB to complain about lack of transparency I guess.
  4. 2021-06-19 14:49 Andrew Rambaut open
    We already discussed this - the 'intermediates' are dubious and from February
  5. 2021-06-19 14:52 Edward C. Holmes
    It's a weird sort of stream of consciousness paper. Very naughty to include an email from the unrelated pangolin study in there. Is that even legal?
  6. 2021-06-19 14:56 Robert F. Garry open
    The WA1 tree - fig 4 and 6 looks fine to me - but me and trees so i really dunno. However the midle guangdong tree looks like :hankey: and forced just based on where WA1 lands, but again i'm no good here at all.
  7. 2021-06-19 14:58 Edward C. Holmes open
    The February part seems important....
  8. 2021-06-19 15:02 Robert F. Garry open
    Unrelated pangolin study - must be either from Alina or a present to Alina. Seriously - not legal - invasion of privacy -unless he got permission somehow from all parties.
  9. 2021-06-19 15:03 Edward C. Holmes open
    Yes, I agree. Can't believe he is doing this.

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