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Slack / Private Message Drop, p.883 [SLACK_001097] · slack_pm:msg:09148

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Yeah, they should really get on it - metagenomic sequencing should be sufficient. It'll be messy, but not a lot of data needed to do meaningful IDs

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2021-05-27 13:34 Edward C. Holmes open

I wonder if they have enough material to shotgun sequence the environmental samples from the market? Might tell them want animals were being sold my looking at the expressed host genes (e.g. COII). Doesn't even need to be the virus positive samples although they would be better.
2021-05-27 13:38 Kristian G. Andersen open

Well, fuck me - so obvious and honestly I had not thought about it. Yes, they should and yes that should be totallydoable.
2021-05-27 13:39 Andrew Rambaut open

Could do a COI amplification - i.e., species barcoding?
2021-05-27 13:47 Edward C. Holmes open

I'll see if I can get George and Weifeng to do it
2021-05-27 13:50 Kristian G. Andersen

Yeah, they should really get on it - metagenomic sequencing should be sufficient. It'll be messy, but not a lot of data needed to do meaningful IDs
2021-05-27 13:52 Andrew Rambaut open

You sure you would be able to do species ID? Pretty unlikely to bring up anything with species level specificity
2021-05-27 13:52 Andrew Rambaut open

COI would be much more sensitive and there is the BOLD database
2021-05-27 13:54 Edward C. Holmes open

It will be messy, but there should be enough to identify the dominant host and at least to exclude humans
2021-05-27 13:58 Robert F. Garry open

You're the man @Eddie Holmes