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Slack / Private Message Drop, p.882 [SLACK_001096] · slack_pm:msg:09147

Page text: p.882 · original PDF

Date
2021-05-27 13:47
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

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I'll see if I can get George and Weifeng to do it

In context

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  1. 2021-05-27 13:10 Kristian G. Andersen open
    Yeah, that's an interesting theory - although it seems like 117 may actually also infect for longer? Did Oli ever do anyof the modeling analyses to try and flesh these differences out a little more?
  2. 2021-05-27 13:34 Edward C. Holmes open
    I wonder if they have enough material to shotgun sequence the environmental samples from the market? Might tell them want animals were being sold my looking at the expressed host genes (e.g. COII). Doesn't even need to be the virus positive samples although they would be better.
  3. 2021-05-27 13:38 Kristian G. Andersen open
    Well, fuck me - so obvious and honestly I had not thought about it. Yes, they should and yes that should be totallydoable.
  4. 2021-05-27 13:39 Andrew Rambaut open
    Could do a COI amplification - i.e., species barcoding?
  5. 2021-05-27 13:47 Edward C. Holmes
    I'll see if I can get George and Weifeng to do it
  6. 2021-05-27 13:50 Kristian G. Andersen open
    Yeah, they should really get on it - metagenomic sequencing should be sufficient. It'll be messy, but not a lot of data needed to do meaningful IDs
  7. 2021-05-27 13:52 Andrew Rambaut open
    You sure you would be able to do species ID? Pretty unlikely to bring up anything with species level specificity
  8. 2021-05-27 13:52 Andrew Rambaut open
    COI would be much more sensitive and there is the BOLD database
  9. 2021-05-27 13:54 Edward C. Holmes open
    It will be messy, but there should be enough to identify the dominant host and at least to exclude humans

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