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Slack / Private Message Drop, pp.700-701 [SLACK_000914] · slack_pm:msg:07351

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Just noticed that dip in early ORF1a - don't know why I didn't notice that before.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-04-13 15:09 Robert F. Garry open

Probably good to keep in mind that GX pango is very similar to SC2 in much of the NTD except IR2 where some of the magic may be happening.
2021-04-13 15:10 Edward C. Holmes open

Good point
2021-04-13 15:29 Andrew Rambaut open

I think clearly WIV were really shit at creating SC2
2021-04-13 15:30 Andrew Rambaut open

GX pango still not nearly as similar as RaTG13: [shared file(s): image.png]
2021-04-13 15:32 Andrew Rambaut

Just noticed that dip in early ORF1a - don't know why I didn't notice that before.
2021-04-13 15:33 Andrew Rambaut open

Looks very similar to the RBD dip
2021-04-13 16:06 Robert F. Garry open

interesting region at the amino acid level as well.
2021-04-13 16:17 Kristian G. Andersen open

Very interesting stuff! Might be worth looking at reversions - do we see more of those in the NTD vs the rest of the spike / genome?
2021-04-13 16:17 Andrew Rambaut open

I assume RmYN02 doesn't drop away like that.