A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Of course A "ancestral" to B so any theory on early emergence has to capture the fact that both lineages associated with wet markets early on....
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Other key fact - just to put it here- WA1 - a traveler from Wuhan to Washington State - lineage A had 3 ancestrasnps per @Andrew Rambaut
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Thanks Bob. I'll head to the desert for a few hours to clear my mind, but I'll comb through this carefully. And yes, agreed about WA1 and I actually speculated about that a while back -https://twitter.com/K_G_Andersen/status/1338993282148302848?s=20
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Interestingly also there is a Malaysian case with exactly the same WA1 haplotype (Malaysia... pangolins...). But probably coincidence.
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2021-03-27 09:45
Kristian G. Andersen
Yup! Take a look at the alignment I shared yesterday... I think it's interesting
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Do we know anymore details about the Malaysian and WA1 cases - seems key.
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Do we know anything more about the epi of the Malaysian or WA1 cases - seems very key. [shared file(s): image.png]
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The Malaysian one you included has an additional SNP difference away from RaTG13 - I am pretty sure there was one that was identical to WA1 (but I did this analysis back in July so have lost all memory of it. Will dig out my notes.
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https://www.seattletimes.com/seattle-news/health/case-of-wuhan-coronavirus-detected-in-washington-state-first-inunited-states/ Here's the news article about WA1