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Slack / Private Message Drop, p.599 [SLACK_000813] · slack_pm:msg:06252

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That seems right. But is the diversity in unsampled humans, unsampled animals or perhaps both. Only A and B lineages made it through the bottleneck.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-03-15 13:45 Robert F. Garry open

Dec 8 is consistent with the graph from the CCDC NEJM paper.
2021-03-15 13:46 Robert F. Garry open

Lots of questions for Kristian: [shared file(s): image.png]
2021-03-15 13:52 Edward C. Holmes open

Pathetic
2021-03-15 14:09 Kristian G. Andersen open

I think there's _a lot_ of early unsampled diversity, which can help explain the A vs B split. Much focus turned to the Huanan market, where super spreading might have occurred, so we end up having very biased sampling early on.
2021-03-15 14:20 Robert F. Garry

That seems right. But is the diversity in unsampled humans, unsampled animals or perhaps both. Only A and B lineages made it through the bottleneck.
2021-03-15 14:24 Robert F. Garry open

Another way to ask the questions: B came from A as Andrew said in the NatMicro paper. But did the split happen inan animal or after the human to animal transfer? Maybe doesn't really matter.