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Slack / Private Message Drop, p.598 [SLACK_000812] · slack_pm:msg:06248

Page text: p.598 · original PDF

Date
2021-03-15 13:45
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

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Dec 8 is consistent with the graph from the CCDC NEJM paper.

In context

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  1. 2021-03-15 13:22 Kristian G. Andersen open
    The grates, totally - and yes, raccoon dogs, or whatever other animal for that matter. Makes perfect sense. But how that fits in with frozen foods, I don't understand. That said, Marion must have something good here, otherwise there's no way she'd go down that path - she's much, much too smart for that. There must be some actual evidence.
  2. 2021-03-15 13:23 Robert F. Garry open
    Then there is the whole lineage A and B = the animals in the Huanan market are lineage B, so how did lineage A get started? The NEJM paper says other case werelinked to other markets, but which ones and which were sequenced Idon't know,.
  3. 2021-03-15 13:26 Robert F. Garry open
    My read as well -on Marion.
  4. 2021-03-15 13:38 Edward C. Holmes open
    Yes, Marion is cautious so they must have something. Hope they release soon. I may have told you but I also heard that they had discounted the Dec 1 case and the earliest known one is now Dec 8. I also think I heard that while this patient had no link to the market his parents had some sort of link to another live animal market. Not sure is this issomething or not.
  5. 2021-03-15 13:45 Robert F. Garry
    Dec 8 is consistent with the graph from the CCDC NEJM paper.
  6. 2021-03-15 13:46 Robert F. Garry open
    Lots of questions for Kristian: [shared file(s): image.png]
  7. 2021-03-15 13:52 Edward C. Holmes open
    Pathetic
  8. 2021-03-15 14:09 Kristian G. Andersen open
    I think there's _a lot_ of early unsampled diversity, which can help explain the A vs B split. Much focus turned to the Huanan market, where super spreading might have occurred, so we end up having very biased sampling early on.
  9. 2021-03-15 14:20 Robert F. Garry open
    That seems right. But is the diversity in unsampled humans, unsampled animals or perhaps both. Only A and B lineages made it through the bottleneck.

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