Slack / Private Message Drop — page 599

[Kristian Andersen] I think there's _a lot_ of early unsampled diversity, which can help explain the A vs B split. Much focus turned to the Huanan market, where super spreading might have occurred, so we end up having very biased sampling early on. [2021-03-15 14:20:04] [Robert Garry] That seems right. But is the diversity in unsampled humans, unsampled animals or perhaps both. Only A and B lineages made it through the bottleneck. [2021-03-15 14:24:50] [Robert Garry] Another way to ask the questions: B came from A as Andrew said in the NatMicro paper. But did the split happen in an animal or after the human to animal transfer? Maybe doesn't really matter. [2021-03-15 16:03:21] [Robert Garry] Daszak speaks: https://www.wbur.org/npr/977527808/who-points-to-wildlife-farms-in-southwest-china-as-likely-source-of-pandemic [2021-03-15 16:07:17] [Eddie Holmes] Fortunately this not the furin cleavage site [shared file(s): IMG_1585.JPG] [2021-03-15 16:18:25] [Eddie Holmes] They were made in China though [2021-03-15 17:02:13] [Eddie Holmes] That NPR story is interesting...all pointing in the same direction [2021-03-15 17:13:44] [Kristian Andersen] I read this channel and see (1) a rat looking thingie rolled up in a bamboo stick, and (2) socks with a furin cleavage site on them - made in China. We have come a long way since we started this channel, gentlemen. [2021-03-15 17:19:21] [Eddie Holmes] If only Billy could see all this? [2021-03-15 17:23:21] [Kristian Andersen] :exploding_head: [2021-03-15 17:49:30] [Eddie Holmes] It's pretty amazing how much Billy hates you. He really thinks you're part of some deep conspiracy. It's just weird, crazy stuff. [2021-03-15 17:51:32] [Kristian Andersen] Yeah, he's even fundraising so he can hate me even more. Happy to support people in their endeavors. [2021-03-15 19:44:04]