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Slack / Private Message Drop, pp.589-590 [SLACK_000803] · slack_pm:msg:06164

Page text: p.589, p.590 · original PDF

Date
2021-03-12 12:38
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

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I post this because it is pretty instructive.

In context

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  1. 2021-03-12 12:18 Edward C. Holmes open
    I'll email them all to you Bob - I'll just make a cup of tea...as long as turning on the kettle is not deemed too dangerous
  2. 2021-03-12 12:22 Edward C. Holmes open
    Had a chat to Linfa and it seems he has more positive pangolins. He's going to run his VirScan-like assays on Tommy's. I think we have 7 positive animals. Of course, that bats may be passing the virus to pangolins does nearly show that virus jump between species in nature. Who would have thought!!
  3. 2021-03-12 12:27 Robert F. Garry open
    Thanks Eddie. I understand that bats etc live in Sri Lanka and other tea growing countries - so yes better to curtailthat overly risky activity going forward. Agreed the pango story is an interesting one on many levels - lots ofimportant CoV evolution and ecology to sort. That is unless the Parisites have their way and all this threateningvirology is stopped.
  4. 2021-03-12 12:33 Edward C. Holmes open
    You're right! I had better stick to coffee...oh no, civets shit coffee beans!!!
  5. 2021-03-12 12:38 Edward C. Holmes
    I post this because it is pretty instructive.
  6. 2021-03-12 12:51 Robert F. Garry open
    Also consistent with another conspiracy theory - all the world's leading virologists (and a few politicians) areshape-shifting space aliens from the future.
  7. 2021-03-12 12:56 Robert F. Garry open
    It's really the only way to explain QTQTNS and some of the other spike motifs in newly sequenced Bat CoVs.
  8. 2021-03-12 13:05 Robert F. Garry open
    Here's the updated Fig. 1 with the new bat viruses. Also noticed that a few of the new ones have a concentration ofS,T,P around the S1/S2 junction. Interestingly, several have several predicted O-linked glycans. So that's a featureof the site that is independent of the SC2 FCS itself. Also worth noting the O-linked glycans near the N terminus aswell. [shared file(s): image.png]
  9. 2021-03-12 13:10 Edward C. Holmes open
    Great stuff Bob. I've just sent you the SI files.

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