COVID-19 Records

Chat message

Slack / Private Message Drop, p.450 [SLACK_000664] · slack_pm:msg:04653

Page text: p.450 · original PDF

Date
2021-01-25 12:59
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut
Topics
Furin cleavage site and molecular features

Recipients on this medium are inferred from channel membership, not per-message addressing.

Amazing. So the Cambobat has the RBD that RaTG13 lost through recombination and is slightly closer than the GD pango by the looks?

Extracted statements

Rule-extracted, not adjudicated. The grade says what may be done with each one; read the document above before relying on any of them.

StatementGradeAttributionStance
So the Cambobat has the RBD that RaTG13 lost through recombination and is slightly closer than the GD pango by the looks? needs context speaker_own questions

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

  1. 2021-01-25 11:55 Robert F. Garry open
    So bottom line a new bat virus that confirms the authenticity of GD pangocov.
  2. 2021-01-25 12:09 Edward C. Holmes open
    Brilliant work Bob! The Cambobatcov paper should be online soon I believe
  3. 2021-01-25 12:14 Robert F. Garry open
    That would be great - have some ideas gelling for an "opinion" piece for Virological. Something along the lines of:New sequences disprove conspiracy theories based on contrived origins of bat coronavirus RatG13 and pangolin coronaviruses.
  4. 2021-01-25 12:44 Edward C. Holmes open
    Love it! Looking forward to having a rant on Twitter
  5. 2021-01-25 12:59 Andrew Rambaut
    Amazing. So the Cambobat has the RBD that RaTG13 lost through recombination and is slightly closer than the GD pango by the looks?
  6. 2021-01-25 13:01 Andrew Rambaut open
    On closer inspection maybe it isn't quite that simple but hey - really interesting
  7. 2021-01-25 13:06 Robert F. Garry open
    Yes, but I think your first approximation is pretty spot on - taking a look at the nucleotide alignment - maybe a case where the protein alignment gives a slightly different picture than the nucleotide alignment. - as ProfBill often saysyou can see the "wobble" codons. That's natural evolution of course not nonsense like the WIV supervillains creatinga fake set of SRA data to cover up their GOF/bioweapons program.

Full conversation →