Slack / Private Message Drop — page 450

[2021-01-25 12:59:18] [Andrew Rambaut] Amazing. So the Cambobat has the RBD that RaTG13 lost through recombination and is slightly closer than the GD pango by the looks? [2021-01-25 13:01:45] [Andrew Rambaut] On closer inspection maybe it isn't quite that simple but hey - really interesting [2021-01-25 13:06:56] [Robert Garry] Yes, but I think your first approximation is pretty spot on - taking a look at the nucleotide alignment - maybe a case where the protein alignment gives a slightly different picture than the nucleotide alignment. - as ProfBill often saysyou can see the "wobble" codons. That's natural evolution of course not nonsense like the WIV supervillains creating a fake set of SRA data to cover up their GOF/bioweapons program. [2021-01-25 14:25:37] [Robert Garry] Certainly strongly supports all you said in Boni2020. [2021-01-25 14:36:07] [Andrew Rambaut] Cool! If you make a nucleotide alignment of the spikes, I would love to take a look. [2021-01-25 14:40:15] [Robert Garry] Will do - on it... [2021-01-25 14:40:32] [Kristian Andersen] Yeah, very interesting - seems like that the "RaTG13 lost the pango RBD" might actually turn out true. Very nice confirmation. [2021-01-25 14:40:57] [Kristian Andersen] Totally unrelated, but this seems very exciting... Can't wait to read the full book [shared file(s): chart.jpg] [2021-01-25 14:41:14] [Kristian Andersen] [Actually, I can wait. Never mind] [2021-01-25 14:42:29] [Robert Garry] Lost me at "Beyond the boyish good looks...." [2021-01-25 14:42:59] [Kristian Andersen] Yeah, not really fair that they didn't say that about Eddie. [2021-01-25 14:44:23] [Kristian Andersen] Here's a preview of the book. Thrilling. [shared file(s): LOCKDOWN_Preview_210121.pdf] [2021-01-25 14:48:35] [Robert Garry]