A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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That's a good analogy to flu - and you're right vaccine update will be needed. Just hoping that most humans can mount a good response to K484.
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Eek + Pooh: ```Accession ID Collection date Submission date Location EPI_ISL_778908 2020-11-30 2021-01-07 North America / USA / Maryland EPI_ISL_791414 2020-11-21 2021-01-08 North America / USA / Maryland EPI_ISL_791426 2020-12-30 2021-01-08 North America / USA / Maryland EPI_ISL_791427 2021-01-01 2021-01-08 North America / USA / Maryland```
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Are they hanging with Nelly too?
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No. Unrelated
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2021-01-18 08:22
Kristian G. Andersen
Interesting. I expect we'll see N501Y pop up on that background shortly.
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Bob, to your point about vaccine updates - yes, absolutely going to be needed. However, what's going to be very different here is that we're going to have a gazillion different (partially) vaccine 'resistant' lineages floating around atthe same time because we have sooooo many infections. Are we going to make an updated vaccine for each? Stick'em all together in a single vaccine? How are we going to prioritize?Until we use NPIs to massively drop infections down, I don't think we'll be successful in this game of whack-a-mole.
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I may be extremely pessimistic here, but by the time we have vaccinated enough people to reach herd immunity thresholds, I'm pretty sure we'll be dealing with almost completely resistant SARS-CoV-2 - and multiple different lineages.
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Maybe true - and it may be time to *start lowering expectations*. It's very possible we'll be in a situation [maybe already there] where the vaccines do not prevent infection or spread but offer some protection from severe disease. AKA flu vaccine. This means getting you ~flu~ CoV vaccine each year or maybe even every 6 months.
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In some ways thou the fact that we're seem the same mutations popping up repeatedly is "reassuring" in the sense that it may not take a gazillion.