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Slack / Private Message Drop, p.379 [SLACK_000593] · slack_pm:msg:03949

Page text: p.379 · original PDF

Date
2021-01-11 13:59
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

Recipients on this medium are inferred from channel membership, not per-message addressing.

It seems like all of these lineages are converging to the same set of mutations

In context

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  1. 2021-01-11 13:57 Andrew Rambaut open
    We have 5 cases of Erik on top of the B117 but they are spontaneous and I doubt driven by antigenic evasion.
  2. 2021-01-11 13:57 Edward C. Holmes open
    Bum.
  3. 2021-01-11 13:58 Andrew Rambaut open
    I can't make the WHO thing but they have Tulio, Trevor and Marion on the evolution panel. I couldn't do it so I got Oli instead.
  4. 2021-01-11 13:58 Andrew Rambaut open
    Really struggling to work out what is going on.
  5. 2021-01-11 13:59 Andrew Rambaut
    It seems like all of these lineages are converging to the same set of mutations
  6. 2021-01-11 13:59 Edward C. Holmes open
    I hope Tulio gets talking combining classification schemes - that will make a fun 7 hours.
  7. 2021-01-11 13:59 Andrew Rambaut open
    Oli will keep him right
  8. 2021-01-11 13:59 Robert F. Garry open
    https://www.fox10phoenix.com/news/fda-to-weigh-half-dosing-moderna-covid-19-vaccines-operation-warp-speed-of ficial-says "These are all reasonable questions to consider and evaluate in clinical trials," the FDA said in a statement on Monday." I agree that the UK dosing strategy is wrong - half dosing makes much more sense with both the prime and the boast. The half and third dosing was already considered in a clinical trial - Moderna's Phase Itrial. Two doses of 10 ug gave essentially the same neut and binding as two doses of 30 ug dose. One dose of 100was terrible and caused al ot more adverse reactions so tjhey stopped it. Hate to be cynical, but I think Moderna isprotecting it's newly hatched golden goose.
  9. 2021-01-11 13:59 Edward C. Holmes open
    :bomb:

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