COVID-19 Records

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Slack / Private Message Drop, p.312 [SLACK_000526] · slack_pm:msg:03277

Page text: p.312 · original PDF

Date
2020-12-14 10:17
Type
chat message · slack
mentioned
Robert F. Garry
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

Recipients on this medium are inferred from channel membership, not per-message addressing.

@Robert Garry Oh, interesting. It's rare - but parallel evolution? [shared file(s): Screen Shot 2020-12-14 at 10.16.54.png]

In context

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  1. 2020-12-14 10:11 Robert F. Garry open
    @Robert Garry Would be surprising if it didn't affect cleavage...
  2. 2020-12-14 10:13 Kristian G. Andersen open
    It's a little weird in that respect - the patient above essentially has no - or very limited - humoral immunity, but thesignatures still look like immune escape - or maybe something else is going on. So yes, even immunecompromisedpatients can shed viruses that may have signatures of immune escape.
  3. 2020-12-14 10:14 Andrew Rambaut open
    @Robert Garry Ooh. Missed that.
  4. 2020-12-14 10:16 Robert F. Garry open
    @Robert Garry That's the one I'd be concerned about.
  5. 2020-12-14 10:17 Kristian G. Andersen
    @Robert Garry Oh, interesting. It's rare - but parallel evolution? [shared file(s): Screen Shot 2020-12-14 at 10.16.54.png]
  6. 2020-12-14 10:18 Kristian G. Andersen open
    @Robert Garry P > H still have FCS, but affects glycans and likely regulation?
  7. 2020-12-14 10:18 Andrew Rambaut open
    Can you send a link to that nextstrain view?
  8. 2020-12-14 10:18 Robert F. Garry open
    @Robert Garry Yeah both of those...
  9. 2020-12-14 10:20 Kristian G. Andersen open
    https://nextstrain.org/ncov/global?c=gt-S_681

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