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Slack / Private Message Drop, p.186 [SLACK_000400] · slack_pm:msg:01922

Page text: p.186 · original PDF

Date
2020-09-20 07:45
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

ppttsTrvrraTSgvsS spike glycoprotein [Pipistrellus abramus bat coronavirus HKU5-related] GenBank: QHA24687.1 best for last FOUR predicted O-glycans.

In context

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  1. 2020-09-20 06:52 Robert F. Garry open
    ```ppttssrlrraTsg``` spike glycoprotein [BtPa-BetaCoV/GD2013] GenBank: AIA62343.1 This one is from another Merbecovirus a little closer to where it might have mattered in China. Bottom line, and maybe it's my myopia for not realizing this before, but there are bat betacoronaviruses inChina that have furin cleavage sites that evolved naturally. This one also has a predicted O-glycan, which may ormay not be used.
  2. 2020-09-20 06:54 Robert F. Garry open
    pptistrlrratSgvS spike [Bat coronavirus (BtCoV/A434/2005)] GenBank: ABG11962.1 Here's the other onefrom china - two predicted O-glycans
  3. 2020-09-20 06:57 Robert F. Garry open
    https://virological.org/t/the-sarbecovirus-origin-of-sars-cov-2-s-furin-cleavage-site/536 makes this conversation a bit more relevant - although that virological post seems to have been one of the factors that sent Alina down the rabbit hole.
  4. 2020-09-20 07:45 Robert F. Garry
    ppttsTrvrraTSgvsS spike glycoprotein [Pipistrellus abramus bat coronavirus HKU5-related] GenBank: QHA24687.1 best for last FOUR predicted O-glycans.

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