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Slack / Private Message Drop, p.186 [SLACK_000400] · slack_pm:msg:01921

Date: 2020-09-20 06:57
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

https://virological.org/t/the-sarbecovirus-origin-of-sars-cov-2-s-furin-cleavage-site/536 makes this conversation a bit more relevant - although that virological post seems to have been one of the factors that sent Alina down the rabbit hole.

Links shared

preprint https://virological.org/t/the-sarbecovirus-origin-of-sars-cov-2-s-furin-cleavage-site/536

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-09-20 06:52 Robert F. Garry open

```ppttssrlrraTsg``` spike glycoprotein [BtPa-BetaCoV/GD2013] GenBank: AIA62343.1 This one is from another Merbecovirus a little closer to where it might have mattered in China. Bottom line, and maybe it's my myopia for not realizing this before, but there are bat betacoronaviruses inChina that have furin cleavage sites that evolved naturally. This one also has a predicted O-glycan, which may ormay not be used.
2020-09-20 06:54 Robert F. Garry open

pptistrlrratSgvS spike [Bat coronavirus (BtCoV/A434/2005)] GenBank: ABG11962.1 Here's the other onefrom china - two predicted O-glycans
2020-09-20 06:57 Robert F. Garry

https://virological.org/t/the-sarbecovirus-origin-of-sars-cov-2-s-furin-cleavage-site/536 makes this conversation a bit more relevant - although that virological post seems to have been one of the factors that sent Alina down the rabbit hole.
2020-09-20 07:45 Robert F. Garry open

ppttsTrvrraTSgvsS spike glycoprotein [Pipistrellus abramus bat coronavirus HKU5-related] GenBank: QHA24687.1 best for last FOUR predicted O-glycans.

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