COVID-19 Records

Private channel session 407

4 messages over 53m, 2020-09-20 – 2020-09-20.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2020-09-20 06:52 Robert F. Garry open PDF p.186
    ```ppttssrlrraTsg``` spike glycoprotein [BtPa-BetaCoV/GD2013] GenBank: AIA62343.1 This one is from another Merbecovirus a little closer to where it might have mattered in China. Bottom line, and maybe it's my myopia for not realizing this before, but there are bat betacoronaviruses inChina that have furin cleavage sites that evolved naturally. This one also has a predicted O-glycan, which may ormay not be used.
  2. 2020-09-20 06:54 Robert F. Garry open PDF p.186
    pptistrlrratSgvS spike [Bat coronavirus (BtCoV/A434/2005)] GenBank: ABG11962.1 Here's the other onefrom china - two predicted O-glycans
  3. 2020-09-20 06:57 Robert F. Garry open PDF p.186
    https://virological.org/t/the-sarbecovirus-origin-of-sars-cov-2-s-furin-cleavage-site/536 makes this conversation a bit more relevant - although that virological post seems to have been one of the factors that sent Alina down the rabbit hole.
  4. 2020-09-20 07:45 Robert F. Garry open PDF p.186
    ppttsTrvrraTSgvsS spike glycoprotein [Pipistrellus abramus bat coronavirus HKU5-related] GenBank: QHA24687.1 best for last FOUR predicted O-glycans.