Chat message

Slack / Private Message Drop, p.85 [SLACK_000299] · slack_pm:msg:00860

Date: 2020-06-18 16:42
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

Recipients on this medium are inferred from channel membership, not per-message addressing.

Yeah, I'm not sure what she's suggesting... Either from human or somebody invented the sequence. Hasn't that sequence been seen from multiple animals by multiple labs?

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-06-18 16:08 Kristian G. Andersen open

Somewhere there's a bat.
2020-06-18 16:18 Kristian G. Andersen open

Speaking of animals and such - I don't know if some of you might want to chime in on this... https://twitter.com/Ayjchan/status/1273632816983683079?s=20
2020-06-18 16:30 Edward C. Holmes open

Not doing Twitter at the moment
2020-06-18 16:36 Edward C. Holmes open

Had a quick look...if Alina is suggesting that the pangolin RBD came from humans she's totally mad (look at the synonymous diversity). 100% clear that that RBD is out there in nature. Not sure what hosts, but definitely in nature.
2020-06-18 16:42 Kristian G. Andersen

Yeah, I'm not sure what she's suggesting... Either from human or somebody invented the sequence. Hasn't that sequence been seen from multiple animals by multiple labs?
2020-06-18 16:48 Edward C. Holmes open

Yes, it has. The two pangolin papers in Nature (different groups) both show the same RBD in the animals from Guangdong.
2020-06-18 16:58 Kristian G. Andersen open

Thought so...
2020-06-18 17:27 Kristian G. Andersen open

This is pretty interesting... [shared file(s): Screen Shot 2020-06-18 at 5.27.34 PM.png]
2020-06-18 17:32 Edward C. Holmes open

But the pangolin sequence is only 'highly identical' at the amino acid level. Not synonymous sites...falls in the expected place at those sites.

Full conversation →