Chat message

Slack / Private Message Drop, p.85 [SLACK_000299] · slack_pm:msg:00859

Date: 2020-06-18 16:36
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker: Edward C. Holmes
Topics: Furin cleavage site and molecular features Natural origin / zoonotic spillover

Recipients on this medium are inferred from channel membership, not per-message addressing.

Had a quick look...if Alina is suggesting that the pangolin RBD came from humans she's totally mad (look at the synonymous diversity). 100% clear that that RBD is out there in nature. Not sure what hosts, but definitely in nature.

Extracted statements

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Statement	Grade	Attribution	Stance
Had a quick look...if Alina is suggesting that the pangolin RBD came from humans she's totally mad (look at the synonymous diversity). 100% clear that that RBD is out there in nature.	own voice, substantive	speaker_own	asserts

Statement

Grade

Attribution

Stance

Had a quick look...if Alina is suggesting that the pangolin RBD came from humans she's totally mad (look at the synonymous diversity). 100% clear that that RBD is out there in nature.

own voice, substantive

speaker_own

asserts

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-06-18 16:07 Kristian G. Andersen open

Human - mink - human - mink - human - human - human - human.
2020-06-18 16:08 Kristian G. Andersen open

Somewhere there's a bat.
2020-06-18 16:18 Kristian G. Andersen open

Speaking of animals and such - I don't know if some of you might want to chime in on this... https://twitter.com/Ayjchan/status/1273632816983683079?s=20
2020-06-18 16:30 Edward C. Holmes open

Not doing Twitter at the moment
2020-06-18 16:36 Edward C. Holmes

Had a quick look...if Alina is suggesting that the pangolin RBD came from humans she's totally mad (look at the synonymous diversity). 100% clear that that RBD is out there in nature. Not sure what hosts, but definitely in nature.
2020-06-18 16:42 Kristian G. Andersen open

Yeah, I'm not sure what she's suggesting... Either from human or somebody invented the sequence. Hasn't that sequence been seen from multiple animals by multiple labs?
2020-06-18 16:48 Edward C. Holmes open

Yes, it has. The two pangolin papers in Nature (different groups) both show the same RBD in the animals from Guangdong.
2020-06-18 16:58 Kristian G. Andersen open

Thought so...
2020-06-18 17:27 Kristian G. Andersen open

This is pretty interesting... [shared file(s): Screen Shot 2020-06-18 at 5.27.34 PM.png]

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