Biosafety and biosecurity

NIAID will be awarding 2 NBLs (BSL-4 labs) and 9 RBLs (BSL-3 labs) on Sept. 30.

Diary Prequel Package, p.82 · original PDF · in context

In small part it will be to reflect on the state of US biosecurity at the 10 yr anniversary of the anthrax attacks.

Gates Package, p.633 · original PDF · in context

We will ask leaders to think ambitiously about the future of biosecurity, and give their views regarding what needs to be done to make progress in the years ahead.

Gates Package, p.633 · original PDF · in context

I told him that that is the biggest difference from todfay when biodefense and biosecurity is a cottage interested with people (Ingesbly et al) and Agencies (DHS) who think about and work on this full time.

Diary Prequel Package, p.282 · original PDF · in context

Tom has a significant problem in that they have been multiple lapses at the CDC with people not adhering to protocol in the experiment with a transfer of select agents such as anthrax, Brucella and influenza.

Diary Prequel Package, p.347 · original PDF · in context

He is under pressure to decrease the number of investigators throughout the country who are working with select agents.

Diary Prequel Package, p.347 · original PDF · in context

Fc On Dec. 22, there was a mess-up at CDC since a worker took and Ebola specimen out of BSL-4 into BSL-2 without inactivating the specimen.

Diary Prequel Package, p.419 · original PDF · in context

Also, discussed on the call the persistent problem of cruise ships in general, which could derail all polasn for containment since they scatter people from all over the world to all over the world.

Tony's Diary Package, p.24 · original PDF · in context

Some disagreement that we had to sort out between ASPR (Kadlec) and CDC (Cetron/Redfield) regarding when to trigger the transition from containment to mitigation.

Tony's Diary Package, p.27 · original PDF · in context

We will need to move to mitigation + containment in Washington State, which has declared state of emergency. 89 cases in USA with more cases each day. 6 deaths in USA Deb Birx on board.

Tony's Diary Package, p.34 · original PDF · in context

All of this is done in BSL-3, so much (much!) less risk of exposure.

Slack / Private Message Drop, p.72 · original PDF · in context

The work in Shi's lab is different - here they are taking bat CoVs and culturing them under BSL-2 in cell lines from different animals - to e.g., understand which ones can infect human cells and what type of mutations that occur inT/C may make them permissive.

Slack / Private Message Drop, p.72 · original PDF · in context

Universities need to ensure students are tested, isolated and cared for on campus or in COVID designated areas to ensure containment and prevent spread both into local community and to hometowns 8.

Tony's Diary Package, p.335 · original PDF · in context

Universities need to ensure students are tested, isolated and cared for on campus or in COVID designated areas to ensure containment and prevent spread both into local community and to hometowns 6.

Tony's Diary Package, p.336 · original PDF · in context

Universities need to ensure students are tested, isolated and cared for on campus or in COVID designated areas to ensure containment and prevent spread both into local community and to hometowns. 8.

Tony's Diary Package, p.337 · original PDF · in context

Apparently they are off to interview and in studio PANEL:• Jason Yat Sen Li• Prof Mary-Louise McLaws - UNSW and advisor to the WHO• Prof Bates Gill - Professor with the Department of Security Studies at Macquarie University• Professor Raina MacIntyre - Global Biosecurity and head of biosecurity program at Kirby Institute• Professor Nikolai Petrovsky - Medicine Flinders University

Slack / Private Message Drop, p.463 · original PDF · in context

Relman, a microbiologist at Stanford University."Raina MacIntyre, professor of biosecurity at the University of New South Wales in Australia, was also surprised to see the idea of a lab accident ruled out so quickly.

Slack / Private Message Drop, p.505 · original PDF · in context

Important to point out that what these people, including Alina, want to do is to SHUTDOWN virology research - stop looking for new viruses and close down all the BSL-3/4 labs.

Slack / Private Message Drop, p.568 · original PDF · in context

Yet Alina would shut down BSL-4 and field workon all viruses in nature.

Slack / Private Message Drop, p.568 · original PDF · in context

For the antiGoF [yes it should be vetted and monitored, which it is] and antiBSL-3/4 [you bet they areregulated] crowd this is all about stirring up the pot again and reviving arguments that they lost. [shared file(s): image.png]

Slack / Private Message Drop, p.614 · original PDF · in context

The problem of course is that there are :clown_face: like Asher (that Fox News interview with the Super-Soldiersabove is really something to watch) that think yeah super villain virologist, Communist china, scary BSL-4 labs, world domination - all adds up.

Slack / Private Message Drop, p.673 · original PDF · in context

Seriously, I can't think of many scientists working in BSL-4 and doing fieldwork that are doing this for the money.

Slack / Private Message Drop, p.713 · original PDF · in context

Yes, although there may well be a difference between BSL-3/4 and BSL-2.

Slack / Private Message Drop, p.849 · original PDF · in context

We have known this since the very beginning - I mentioned it on our very first call that I was concerned about themcollecting and growing sampling from bats under BSL-2.

Slack / Private Message Drop, p.1033 · original PDF · in context

This work is exactly that.To be clear, this type of work is approved under BSL-2 almost universally - I can do it at my lab here at Scripps (and,in fact, we have).

Slack / Private Message Drop, p.1033 · original PDF · in context

Make it clear that: (1) separate debate on biosafety in the light of how widespread SARSr viruses are, and (2) that continued investigations to understand their emergence is required, including figuring out exactly how SC2 poppedup (and SC1 for that matter).

Slack / Private Message Drop, p.1034 · original PDF · in context

And the reason that is, is that they've published papers saying that they did their work at BSL-2.

Baric Transcribed Interview (Redacted), p.67 · original PDF · in context

So there are many more laboratory-acquired infections at BSL-2 than at BSL-3.

Baric Transcribed Interview (Redacted), p.67 · original PDF · in context

And so if you're working with viruses than use human receptors and growing human cells, and you're doing it at BSL-2, you DC.Scheduling@LexitasLegal.com cannot ever conclusively say that there was not a laboratory leak.

Baric Transcribed Interview (Redacted), p.67 · original PDF · in context