Chat message

Slack / Private Message Drop, p.1102 [SLACK_001316] · slack_pm:msg:11490

Date: 2022-04-05 07:11
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

The core structures of the protein - that can be seen here as either beta sheet sandwiches or alpha helices are MUCH less variable. Again no surprise, but sets limits on how much Spike can vary.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2022-04-05 07:05 Robert F. Garry open

THat's a lot of travel. I'm loooking forward maybe someday to getting back my wings too.
2022-04-05 07:05 Robert F. Garry open

After finishing up the current papers might be worth parking this somewhere in an actual manuscript.
2022-04-05 07:07 Edward C. Holmes open

Travel is not what it was. I'm definitely not going back to the old days.
2022-04-05 07:08 Robert F. Garry open

NO surprise that the indel regions of Spike are all in the surface exposed loops shown here in spheres. These regions probably also define "blocks" that can be exchanged in and out during recombination. [shared file(s): image.png]
2022-04-05 07:11 Robert F. Garry

The core structures of the protein - that can be seen here as either beta sheet sandwiches or alpha helices are MUCH less variable. Again no surprise, but sets limits on how much Spike can vary.
2022-04-05 07:38 Robert F. Garry open

@Eddie Holmes hope you're still OK with having a cameo on the maybe Science cover. [shared file(s): 2022.04.04_garry lab cover_render.pdf]
2022-04-05 07:40 Andrew Rambaut open

That is amazing!!
2022-04-05 07:41 Edward C. Holmes open

Ha, I love it
2022-04-05 07:46 Robert F. Garry open

Glad you like it - we went through several versions - ultimately going with a close-up of the Wall of crazy - my originalsketch was too much like a Where's Waldo and too much insider stuff (although I liked it). Science would not have liked animals in cages on the cover. [shared file(s): Garry Lab Science Cover_Detail_Concepts v2 (2).pdf]

Full conversation →