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Slack / Private Message Drop, p.1102 [SLACK_001316] · slack_pm:msg:11489

Date: 2022-04-05 07:08
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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NO surprise that the indel regions of Spike are all in the surface exposed loops shown here in spheres. These regions probably also define "blocks" that can be exchanged in and out during recombination. [shared file(s): image.png]

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2022-04-05 06:51 Edward C. Holmes open

Great! I've just been in a plane for 17 hours. Currently in transit in Darwin.
2022-04-05 07:05 Robert F. Garry open

THat's a lot of travel. I'm loooking forward maybe someday to getting back my wings too.
2022-04-05 07:05 Robert F. Garry open

After finishing up the current papers might be worth parking this somewhere in an actual manuscript.
2022-04-05 07:07 Edward C. Holmes open

Travel is not what it was. I'm definitely not going back to the old days.
2022-04-05 07:08 Robert F. Garry

NO surprise that the indel regions of Spike are all in the surface exposed loops shown here in spheres. These regions probably also define "blocks" that can be exchanged in and out during recombination. [shared file(s): image.png]
2022-04-05 07:11 Robert F. Garry open

The core structures of the protein - that can be seen here as either beta sheet sandwiches or alpha helices are MUCH less variable. Again no surprise, but sets limits on how much Spike can vary.
2022-04-05 07:38 Robert F. Garry open

@Eddie Holmes hope you're still OK with having a cameo on the maybe Science cover. [shared file(s): 2022.04.04_garry lab cover_render.pdf]
2022-04-05 07:40 Andrew Rambaut open

That is amazing!!
2022-04-05 07:41 Edward C. Holmes open

Ha, I love it

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