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Slack / Private Message Drop, p.1031 [SLACK_001245] · slack_pm:msg:10775

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Back in the old Beta days we were discussing this critter:https://en.wikipedia.org/wiki/Genet_(animal)

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2021-11-26 09:07 Robert F. Garry open

CHeck out the figure in the other channel - 7-of 7 mutations seen in rodents are in Nu - that's unlikely....
2021-11-26 09:08 Andrew Rambaut open

We are working with Tulio on this so I would prefer not to broaden it out too much.
2021-11-26 09:08 Robert F. Garry open

Oh yeah!
2021-11-26 09:09 Andrew Rambaut open

I got excited because the 679K mutation is also seen in C.1.2 (i.e., in South Africa) _but_ it is a different codon in Nuand doesn't have 681H so probably convergent
2021-11-26 09:09 Andrew Rambaut

Back in the old Beta days we were discussing this critter:https://en.wikipedia.org/wiki/Genet_(animal)
2021-11-26 09:10 Andrew Rambaut open

Apparently is often commensal with humans (living in roofs etc).
2021-11-26 09:11 Andrew Rambaut open

I know that Civets are not a favoured host but again, perhaps that would explain the RBD - i.e. mustelids are closerto humans, civets require more adaptation.
2021-11-26 09:11 Andrew Rambaut open

Rodents would also be likely, obviously.
2021-11-26 09:13 Robert F. Garry open

Nu does have Y505H previously seen in a lion...plus a few other catty ones.