COVID-19 Records

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Slack / Private Message Drop, p.947 [SLACK_001161] · slack_pm:msg:09851

Page text: p.947 · original PDF

Date
2021-06-19 13:30
Type
chat message · slack
mentioned
Kristian G. Andersen
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

Recipients on this medium are inferred from channel membership, not per-message addressing.

@Kristian Andersen let me know if you want to have call later today/tomorrow before Tony/FrancisII - interested inyour thoughts

In context

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  1. 2021-06-19 13:30 Robert F. Garry
    @Kristian Andersen let me know if you want to have call later today/tomorrow before Tony/FrancisII - interested inyour thoughts
  2. 2021-06-19 14:08 Kristian G. Andersen open
    Yeah cutting my trip short for this and will be back tonight. Can we set up a call Sunday am with Andrew too?
  3. 2021-06-19 14:09 Kristian G. Andersen open
    I haven't looked at any of this yet
  4. 2021-06-19 14:44 Robert F. Garry open
    "The second explanation, which was proposed in a blog post by Garry (2021) and amplified by a popular podcast (Racaniello _et al._ 2021), is that there were multiple zoonoses from distinct markets, with the Huanan Seafood Market being the source of viruses in clade B, and some other market being the source of viruses that lack the T8782C and C28144T mutations. However, inspection of Fig- ure 4 shows that clade B is connected to viruses lacking T8782C and C28144T by single mutational steps via other human iso- lates, so this explanation requires not only positing two markets with two progenitors differing by just two mutations, but also the exceedingly improbableevolution of one of these progenitors towards the other after it had jumped to humans." Actually no - simple to see how the mutations might have become fixed in the progression -I think the take-home is JB is dead set that Rambautis wrong and actually B came before A. Because? [shared file(s): image.png]
  5. 2021-06-19 14:45 Edward C. Holmes open
    Is this something or nothing? I can't quite get my head around it.

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