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Slack / Private Message Drop, p.895 · slack_pm:msg:09287

Page text: p.895 · original PDF

Date
2021-05-29 18:32 (hour precision)
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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Is there anywhere to confirm the sequences are internal and not just from NCBI?

In context

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  1. 2021-05-29 18:32 Edward C. Holmes open
    This is also the first reported tree with SARS-CoV-2 in.
  2. 2021-05-29 18:32 Edward C. Holmes open
    Might not be much but it is at least consistent.
  3. 2021-05-29 18:32 Kristian G. Andersen open
    Ahhh, I see what you're saying - this tree contains *everything* relevant they have, including RaTG13, which is very very close if you only consider RdRp. If she was concerned about similarity because it came from the lab, she would have taken out 4991 - it's very very close in the tree, but once you have the full sequence, you know it ain't it, but you don't from just the RdRp fragment.
  4. 2021-05-29 18:32 Edward C. Holmes open
    Yes, that's it.
  5. 2021-05-29 18:32 Kristian G. Andersen
    Is there anywhere to confirm the sequences are internal and not just from NCBI?
  6. 2021-05-29 18:32 Kristian G. Andersen open
    If the former, this is the 'effing SMOKING GUN of NOT lab escape.
  7. 2021-05-29 18:32 Edward C. Holmes open
    Let me check with i
  8. 2021-05-29 18:32 Kristian G. Andersen open
    SLACK_001110 That'd be great. If I looked at that tree and I was Shi, my first thought would be - FUCK, did 4991 get out? Yet, she/they decided not to hide the similarity (of course, it would have been noticed anyway because 4991 was ina public database, but there's just no way they'd be thinking that way).
  9. 2021-05-29 18:32 Kristian G. Andersen open
    The sequences all have NCBI accession numbers, so probably from NCBI.

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