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Slack / Private Message Drop, p.895 · slack_pm:msg:09285

Date: 2021-05-29 18:32 (hour precision)
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

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Ahhh, I see what you're saying - this tree contains *everything* relevant they have, including RaTG13, which is very very close if you only consider RdRp. If she was concerned about similarity because it came from the lab, she would have taken out 4991 - it's very very close in the tree, but once you have the full sequence, you know it ain't it, but you don't from just the RdRp fragment.

In context

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2021-05-29 18:32 Kristian G. Andersen open

Which part?
2021-05-29 18:32 Edward C. Holmes open

This is the earliest document on the outbreak from Shi's lab I think. She said that they sequenced SARS-CoV-2 and then screened their databases to see what matched. The only match they had was 4991/RaTG13. No evidence ofanything as close that they then deleted. It also confirms the Addendum to her Nature paper.
2021-05-29 18:32 Edward C. Holmes open

This is also the first reported tree with SARS-CoV-2 in.
2021-05-29 18:32 Edward C. Holmes open

Might not be much but it is at least consistent.
2021-05-29 18:32 Kristian G. Andersen

Ahhh, I see what you're saying - this tree contains *everything* relevant they have, including RaTG13, which is very very close if you only consider RdRp. If she was concerned about similarity because it came from the lab, she would have taken out 4991 - it's very very close in the tree, but once you have the full sequence, you know it ain't it, but you don't from just the RdRp fragment.
2021-05-29 18:32 Edward C. Holmes open

Yes, that's it.
2021-05-29 18:32 Kristian G. Andersen open

Is there anywhere to confirm the sequences are internal and not just from NCBI?
2021-05-29 18:32 Kristian G. Andersen open

If the former, this is the 'effing SMOKING GUN of NOT lab escape.
2021-05-29 18:32 Edward C. Holmes open

Let me check with i

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