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Slack / Private Message Drop, p.751 [SLACK_000965] · slack_pm:msg:07866

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Agreed. It's a very interesting question, but exceptionally hard to answer - working on some very early attempts with Joel + Marc.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-05-05 10:27 Robert F. Garry open

https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msab118/6257226 "We have made available the proCoV2 genome sequence in FastA format at http://igem.temple.edu/COVIDn19, which is the same as the NCBI reference genome with base differences corresponding to 1 - 3 mutations at positions 18060, 8782, and 28144, as discussed in the main text. In this mutation graph, COI for each variant is shown next to the arrow.
2021-05-05 10:27 Robert F. Garry open

Lineage A?
2021-05-05 10:33 Kristian G. Andersen open

No, B. I'm perplexed by that paper - didn't read it in detail, but I don't think they can really do what they do. So many reversions observed during the pandemic and associated dates and biases in sequencing early on likely majorlybias interpretation. @Andrew Rambaut, did you get a chance to read it?
2021-05-05 10:37 Andrew Rambaut open

I couldn't face it. I would just get annoyed
2021-05-05 10:42 Kristian G. Andersen

Agreed. It's a very interesting question, but exceptionally hard to answer - working on some very early attempts with Joel + Marc.