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Slack / Private Message Drop, p.751 [SLACK_000965] · slack_pm:msg:07862

Page text: p.751 · original PDF

Date
2021-05-05 10:27
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Furin cleavage site and molecular features

Recipients on this medium are inferred from channel membership, not per-message addressing.

https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msab118/6257226 "We have made available the proCoV2 genome sequence in FastA format at http://igem.temple.edu/COVIDn19, which is the same as the NCBI reference genome with base differences corresponding to 1 - 3 mutations at positions 18060, 8782, and 28144, as discussed in the main text. In this mutation graph, COI for each variant is shown next to the arrow.

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  1. 2021-05-05 09:37 Andrew Rambaut open
    (I didn't click on the link)
  2. 2021-05-05 09:41 Kristian G. Andersen open
    Click it!!!
  3. 2021-05-05 10:22 Andrew Rambaut open
    Malware to crack my computer and get access to all the incriminating messages from CCP.
  4. 2021-05-05 10:25 Robert F. Garry open
    May be better to just revert to using your HP-87. Probably good to go for another 30-40 years at least.
  5. 2021-05-05 10:27 Robert F. Garry
    https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msab118/6257226 "We have made available the proCoV2 genome sequence in FastA format at http://igem.temple.edu/COVIDn19, which is the same as the NCBI reference genome with base differences corresponding to 1 - 3 mutations at positions 18060, 8782, and 28144, as discussed in the main text. In this mutation graph, COI for each variant is shown next to the arrow.
  6. 2021-05-05 10:27 Robert F. Garry open
    Lineage A?
  7. 2021-05-05 10:33 Kristian G. Andersen open
    No, B. I'm perplexed by that paper - didn't read it in detail, but I don't think they can really do what they do. So many reversions observed during the pandemic and associated dates and biases in sequencing early on likely majorlybias interpretation. @Andrew Rambaut, did you get a chance to read it?
  8. 2021-05-05 10:37 Andrew Rambaut open
    I couldn't face it. I would just get annoyed
  9. 2021-05-05 10:42 Kristian G. Andersen open
    Agreed. It's a very interesting question, but exceptionally hard to answer - working on some very early attempts with Joel + Marc.

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