Chat message

Slack / Private Message Drop, p.634 [SLACK_000848] · slack_pm:msg:06649

Date: 2021-03-25 22:57
Type: chat message · slack
recipient: Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker: Kristian G. Andersen

Recipients on this medium are inferred from channel membership, not per-message addressing.

Update files here - some of these mutations are interesting. A few convergent mutations with B.1.1.7 / B.1.351 / P.1(like Pooh and Eek) but also some of the usual suspects missing - Doug and Phil are missing, because it sproutedoff a very basal lineage. However, N501Y and del3675-3677 also missing - I bet D614G is required for N501Y...This is one messed up variant - although I'm not sure this is a particularly concerning set of mutations - but :man-shrugging: [shared file(s): Screen Shot 2021-03-25 at 10.52.33 PM.png, tanzania_variant_snps.xlsx]

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-03-25 22:57 Kristian G. Andersen

Update files here - some of these mutations are interesting. A few convergent mutations with B.1.1.7 / B.1.351 / P.1(like Pooh and Eek) but also some of the usual suspects missing - Doug and Phil are missing, because it sproutedoff a very basal lineage. However, N501Y and del3675-3677 also missing - I bet D614G is required for N501Y...This is one messed up variant - although I'm not sure this is a particularly concerning set of mutations - but :man-shrugging: [shared file(s): Screen Shot 2021-03-25 at 10.52.33 PM.png, tanzania_variant_snps.xlsx]
2021-03-25 23:20 Kristian G. Andersen open

... and finally, I should add - several of these mutations appear to be reversions back to bat virus. I'll take a closer look tomorrow. But I'd _does_ bring me back to the speculation of a potential animal reservoir...

Full conversation →