Slack / Private Message Drop — page 634

[2021-03-25 17:34:13] [Robert Garry] Yeah - it's a seafood market, but I'm glad GG admitted that they were selling wild illegal animals there. [2021-03-25 17:47:34] [Kristian Andersen] Yeah, sorry, missed the darn talk! [2021-03-25 17:51:30] [Eddie Holmes] Ah, good for George. [2021-03-25 17:52:00] [Robert Garry] I asked him as nice question about the animals in the market for you and complemented him on a good talk. NO Cts values however. [2021-03-25 17:54:14] [Robert Garry] GG did talk about culturing the virus from one of the market samples and using it in other experiments. [2021-03-25 19:32:36] [Kristian Andersen] This isn't fucking normal! [shared file(s): Screen Shot 2021-03-25 at 7.32.08 PM.png] [2021-03-25 19:33:38] [Kristian Andersen] That's an N/S of >3 [2021-03-25 19:38:06] [Kristian Andersen] Ts/Tv of 1.8 - that is highly elevated Tv. [2021-03-25 20:48:24] [Kristian Andersen] shared file(s): tanzania_variant_snps.xlsx [2021-03-25 22:57:32] [Kristian Andersen] Update files here - some of these mutations are interesting. A few convergent mutations with B.1.1.7 / B.1.351 / P.1 (like Pooh and Eek) but also some of the usual suspects missing - Doug and Phil are missing, because it sprouted off a very basal lineage. However, N501Y and del3675-3677 also missing - I bet D614G is required for N501Y... This is one messed up variant - although I'm not sure this is a particularly concerning set of mutations - but :man-shrugging: [shared file(s): Screen Shot 2021-03-25 at 10.52.33 PM.png, tanzania_variant_snps.xlsx] [2021-03-25 23:20:34] [Kristian Andersen] ... and finally, I should add - several of these mutations appear to be reversions back to bat virus. I'll take a closer look tomorrow. But I'd _does_ bring me back to the speculation of a potential animal reservoir... [2021-03-26 05:20:34] [Robert Garry] Alina unpinned her wall-of-crazy tweetorial. Now she just wants to debate @Kristian Andersen in a live forum - apparently to the death.