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Slack / Private Message Drop, p.587 [SLACK_000801] · slack_pm:msg:06138

Page text: p.587 · original PDF

Date
2021-03-11 11:20
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes

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Thanks Bob! There's another close bat CoV on GISAID - PrC31 I think. Also from Yunnan. This is from the China CDC. Paper being written up apparently.

In context

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  1. 2021-03-11 11:09 Robert F. Garry open
    Origins and evolution of SARS-CoV-2? Could include some things about pathways to the variants as well I think. Itall relates - SC2 more pantropic than human adapted, but its getting better at infecting us.
  2. 2021-03-11 11:14 Robert F. Garry open
    Also working on an update to Holmes2021 virological post - including the new Weifeng viruses from the garden. [shared file(s): image.png]
  3. 2021-03-11 11:19 Robert F. Garry open
    O-glycans included here in the N terminus, but also some "new" ones near the S1/S2 junction. Hard to think that thisis all just coincidence.
  4. 2021-03-11 11:20 Robert F. Garry open
    Also updating Figure 2, but not quite there yet.
  5. 2021-03-11 11:20 Edward C. Holmes
    Thanks Bob! There's another close bat CoV on GISAID - PrC31 I think. Also from Yunnan. This is from the China CDC. Paper being written up apparently.
  6. 2021-03-11 11:22 Robert F. Garry open
    Will check it out!
  7. 2021-03-11 11:37 Robert F. Garry open
    It's VERY close to RpYN06 in spike. [shared file(s): image.png]
  8. 2021-03-11 11:45 Robert F. Garry open
    Very close [shared file(s): image.png]
  9. 2021-03-11 11:46 Kristian G. Andersen open
    @Andrew Rambaut - reading the most recent PHE report on VOCs/VOIs (so good!), is it fair to say that non-B.1.1.7 VOCs just aren't that successful in the UK compared to B.1.1.7? Enough data to make that conclusion? Separately, is it fair to say that B.1.1.7 lineages with mutations such as E484K don't appear to be any more successful than 'vanilla' B.1.1.7?

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